About The Study: In this national multicenter cohort study of inpatients with COVID-19, early administration of dexamethasone was associated with significantly reduced odds of mortality or discharge to hospice in those requiring supplemental oxygen or mechanical ventilation and/or extracorporeal membrane oxygenation but not in those requiring no supplemental oxygen or noninvasive positive pressure ventilation. These results support the continued use of systemic dexamethasone in patients hospitalized with COVID-19.
Authors: Laine E. Thomas, Ph.D., of Duke University in Durham, North Carolina, is the corresponding author.
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(doi:10.1001/jamanetworkopen.2023.8516)
