WaterPuzzle Makes Hydrogen Bonds Easier for Students to Learn

Water is one of the most essential components of life and many of its unique properties arise from interactions between its molecules. Hydrogen bonds influence water's physical properties, contribute to the formation of ice crystals, and are crucial for normal biological processes. Understanding these interactions is fundamental to chemistry, physics, and biology. However, because molecular interactions take place at a scale that cannot be directly observed, students may struggle to visualize how individual molecules connect and organize into larger structures.

Traditional molecular models help students understand the arrangement of atoms within molecules, but most often they cannot demonstrate how separate molecules interact. Although magnetic models have previously been developed to represent intermolecular interactions, there exists an opportunity to use them more extensively to explore the structural properties of water through guided classroom activities. Recognizing this challenge, researchers sought to make chemistry more intuitive through physical exploration rather than relying exclusively on textbooks and static illustrations.

In an effort to help students better understand these interactions, a researcher team led by Professor Jiro Kondo, Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, developed WaterPuzzle, a magnetic molecular model designed to help students investigate hydrogen bonding and molecular interactions in water.

The study was available online on September 30, 2026, and published in Volume 103 of The Journal of Chemical Education on October 13, 2026, and was co-authored by Yuna Ohtani (Graduate School of Science and Technology, Sophia University), Tania Guadalupe Peñaflor Galindo (Department of Materials and Life Sciences, Sophia University), and Shota Nakamura (StudioMIDAS Inc.).

In Kondo's words, "Our motivation came from observing that many students struggle to understand chemistry's underlying principles or fully appreciate the subject through conventional teaching methods. We believe that a more intuitive understanding of the laws of nature could help students develop a stronger affinity for chemistry."

WaterPuzzle consists of 3D-printed water molecule models attached using small neodymium magnets. The magnetic sites represent hydrogen-bond donors and acceptors, with attractive and repulsive forces guiding the pieces towards hydrogen-bond-like arrangements. The researchers developed structured educational activities in which students assemble molecules, construct hydrogen-bond networks, and explore molecular geometry and crystal structures. The STL files required to print the models are provided free of charge, allowing educators to easily fabricate them using commonly available 3D printers.

These activities allow students to explore the tetrahedral arrangement of hydrogen-bonding sites around water molecules and construct the hexagonal networks characteristic of Ice Ih, which is the most common crystalline form of ice under atmospheric conditions. By stacking hexagonal rings, they can investigate how ice forms an open framework that forms the basis for its lower density compared with liquid water. Students can also explore other ice structures, including Ice Ic, Ice II, Ice III, and Ice XVII. Further, combining WaterPuzzle with the previously developed BasePairPuzzle model allows students to understand how water interacts with nucleobases and forms hydration shells around biological molecules.

While WaterPuzzle primarily helps in practically understanding molecular structures, it also acts as a tool for educators to encourage active learning and scientific inquiry. Its easy-to-use design could promote active learning and scientific inquiry. Its accessible design could help make complex concepts easier to explore, while free printing files support wider classroom adoption.

WaterPuzzle offers a hands-on approach to making chemistry more intuitive, accessible, and enjoyable. By allowing students to physically construct and investigate molecular networks, the activity could help them develop a deeper appreciation of the molecular interactions that shape the natural world and contribute to stronger chemical literacy.

Reference

About Professor Jiro Kondo from Sophia University

Jiro Kondo is a Professor in the Department of Materials and Life Sciences at Sophia University in Tokyo, Japan. With a PhD from the Tokyo Institute of Technology in 2004 and postdoctoral research at the University of Strasbourg, his main research focus is in biophysics and structural biology, with particular emphasis on the three-dimensional structures of DNA and RNA and their applications in medicine and nanotechnology. Professor Kondo has also developed innovative educational tools, including BasePairPuzzle and WaterPuzzle, which use magnetic molecular models to make complex scientific concepts more intuitive and accessible to students.

About Sophia University

Established as a private Jesuit-affiliated university in 1913, Sophia University is one of the most prestigious universities located in the heart of Tokyo, Japan. Imparting education through 29 departments in 9 faculties and 25 majors in 10 graduate schools, Sophia hosts more than 13,000 students from around the world.

Conceived with the spirit of "For Others, With Others," Sophia University truly values internationality and neighborliness, and believes in education and research that go beyond national, linguistic, and academic boundaries. Sophia emphasizes on the need for multidisciplinary and fusion research to find solutions for the most pressing global issues like climate change, poverty, conflict, and violence. Over the course of the last century, Sophia has made dedicated efforts to hone future-ready graduates who can contribute their talents and learnings for the benefit of others, and pave the way for a sustainable future while "Bringing the World Together."

Website: https://www.sophia.ac.jp/eng/