Three Cambridge researchers are among 77 early-career researchers who have been awarded a total of £120 million to lead vital research, collaborate with innovators and develop their careers as the research and innovation leaders of the future.
Cambridge researchers Dr Claudia Bonfio, Dr Akshay Deshmukh and Dr Elizabeth Radford have been awarded UKRI Future Leader Fellowships, which provides up to seven years of support to enable them to tackle ambitious programmes or multidisciplinary questions, and new or emerging research and innovation areas and partnerships.
Dr Claudia Bonfio's lab in the Department of Biochemistry studies how life emerges from non-living matter and tries to answer this question by designing and building active primitive cells. Her Future Leader Fellowship project addresses this evolutionary question through an approach that bridges chemistry and biophysics, by investigating how the synergy between primitive lipids and peptides led to the emergence of membrane proteins - a hallmark of living cells.
Dr Akshay Deshmukh is returning to Cambridge's Department of Chemical Engineering and Biotechnology from MIT to take up his Future Leader Fellowship. To reach net zero by 2050, we will require seven times more critical metals than we produce today. Current extraction methods use large amounts of energy, water, chemicals, and land. During his Fellowship, Deshmukh will develop new processes to recover metals from sources like brines and recycling streams. His research combines experiments, spectroscopy, and mechanistic studies to create a framework for designing next-generation membranes, and aims to speed up the development of cheaper, more sustainable separation technologies.
Dr Elizabeth Radford is a paediatric neurologist based in the Department of Paediatrics, whose research is working to accelerate diagnosis and expand the treatment options for children affected by neurodevelopmental genetic conditions. Everyone carries small genetic changes, and while most are harmless, some disrupt how the proteins in our cells work and can affect a child's development. However, it isn't always clear which changes cause problems, making diagnosis slow and uncertain. During her Fellowship, Radford will study thousands of genetic changes by recreating them in human cells grown in the lab. This will show which changes damage proteins, helping doctors interpret genetic tests and provide earlier diagnoses, and paving the way for future treatments.
UK Research and Innovation's (UKRI) Future Leaders Fellowships fund allows universities and businesses to develop talented early career researchers and innovators and attract new people to their organisations, including from overseas.
Out of the successful applications, thirteen projects are led by businesses and funded by Innovate UK.
To support excellent research and innovation wherever it arises and to facilitate movement of people and projects between sectors, FLF fellows are based in the most appropriate environment for their projects, be that universities, businesses, charities, or other independent research organisations.
The Fellowship allows the individual to devote their time to tackle challenging research and innovation problems and to develop their careers as they become the next wave of world-class research and innovation leaders.
The Fellowship also allows recipients access to the FLF Development Network, which provides specialised leadership training, access to networks, workshops, mentors, one-to-one coaching, and opportunities for additional seed-funding for collaborative projects.
"UKRI's Future Leaders Fellowships provide researchers and innovators with long-term support and training to embark on large and complex research programmes, to address key national and global challenges," said Frances Burstow, Director of Talent and Skills at UKRI. "The programme supports the research and innovation leaders of the future to transcend disciplinary and sector boundaries, bridging the gap between academia and business. UKRI supports excellence across the entire breadth of its remit, supporting early-career researchers to lessen the distance from discovery to real world impact."
"UKRI's Future Leaders Fellowships offer long-term support to outstanding researchers, helping them turn bold ideas into innovations that improve lives and livelihoods in the UK and beyond," said UKRI Chief Executive, Professor Sir Ian Chapman. "These fellowships continue to drive excellence and accelerate the journey from discovery to public benefit. I wish them every success."
