Who Needs COVID Vaccine and Who Can Skip It?

The COVID pandemic feels like a long time ago. Now, we have widespread immunity from vaccination and natural infection. And getting COVID is less risky than it was five years ago.

But COVID can still lead to hospitalisation and deaths in older people, pregnant women and those with underlying chronic diseases, such as asthma or heart disease.

Each year in Australia, COVID is estimated to cause 2,000-5,000 deaths and more than 100,000 hospitalisations. COVID was the leading infectious cause of death in Australia between 2020-2025 , with 4,613 deaths in 2023, 3,908 in 2024 and 1,722 deaths in 2025.

Vaccination continues to be one of the most effective ways to prevent deaths and serious complications from COVID.

So who should get a COVID vaccine, and how often?

Older adults and those with underlying conditions

COVID vaccines are recommended for those at risk of getting severe disease:

  • adults 75 years and over are recommended to get a COVID booster every six months

  • adults aged 65-74 years without underlying conditions are recommended to get a booster every 12 months

  • adults aged 18-64 with underlying conditions are recommended to get a booster every 12 months.

A study found that in 2021-22 people living in residential facilities accounted for 21% of " excess deaths " (beyond what would usually be seen) in Australia, despite making up less than 1% of the population. Aged care residents live in close proximity to each other and rely on care workers and nurses who attend large number of residents, meaning COVID infections can easily spread.

People who live in a residential aged care facility are therefore recommended to get a booster every six months.

What about pregnant women?

COVID vaccines are also recommended for pregnant women who have never been vaccinated .

In a study looking at more than 100,000 mother-baby pairs , vaccinated people were less likely to have pregnancy complications.

Otherwise healthy, previously vaccinated pregnant women are no longer recommended to have boosters. Unlike during the pandemic, pregnant women who are otherwise healthy are now at low risk risk of getting severe disease or pregnancy complications from COVID.

Why do at-risk groups need to keep getting vaccinated?

In Australia, older adults are offered routine immunisations for influenza, pneumococcal disease, shingles and RSV. The World Health Organization recommends COVID vaccines be part of these kinds of routine immunisation programs for adults and high-risk groups. This will prevent them from getting severe disease.

There is some evidence that immunity from vaccines might decline over a period of around six months .

But there are high levels hybrid immunity in the population, from previous infections and vaccinations at different times, so this declining immunity is less of a concern than in previous years.

Optional: other adults

Younger people and otherwise healthy people are at generally lower risk of getting severe disease.

COVID vaccines are available (rather than recommended) every 12 months, for adults 18-64 years. This means it's safe to get additional boosters and you can have one if you decide it's right for you. You can also discuss this with your medical provider.

Like all vaccines, COVID boosters come with common, short-term side effects, such as fever, pain at the injection site and tiredness.

Severe adverse events , such as heart inflammation are extremely rare, with one to two cases per 100,000 vaccinations. These risks are also weighed as part of the risk and benefits decision when recommending additional boosters. You can also talk to your medical provider about these.

For otherwise healthy people who have been previously vaccinated , the risk of getting severe disease from COVID is low. So it's up to the individual to make the choice. Additional boosters are safe and protective, but the added benefits are smaller.

This is different to earlier years of the pandemic where there was very little immunity in the population, both from natural infection and vaccination. Now most people in the community have some level of immunity against COVID.

What about children?

Typically, kids with COVID develop mild, cold-like symptoms which resolve in two to seven days. Severe disease is less common .

However, children with underlying conditions such as obesity, or chronic heart, lung, or neurological problems are at greater risk of becoming more unwell from COVID.

A primary course of COVID vaccine is available for children aged six months and over with conditions that increases their risk of severe COVID.

Booster vaccines are available for children aged 5-17 years who are severely immunocompromised every 12 months.

What vaccines are available?

The main vaccine available for use in Australia is the Comirnarty vaccine. Two types are available: one against the SARS-CoV-2 Omicron JN.1 and the other against the Omicron LP.8.1 variant.

A study from the United States found the JN.1 formulation was more than 40% effective against hospitalisations in immunocompromised adults aged 65 years or over.

Meanwhile, a recent European study found vaccination with the LP8.1 formulation was also effective in generating antibodies against the NB.1.8.1 variant - which is currently circulating in Australia - as well as the globally dominant XFG variant.

So if you're in one of the recommended groups, it's worth getting either vaccine, as the dominance of these variants can change month to month and in different locations.

While these dominant variants all come from the Omicron lineage, health experts globally continue to monitor the evolution of COVID strains so they can keep a watch on its spread, disease severity and performance of vaccines.

The Conversation

Meru Sheel receives funding from Australian Government Department of Foreign Affairs and Trade and the National Health and Medical Research Council (NHMRC). She is a member of the World Health Organization's Immunization and Vaccines related Implementation Research Advisory Committee (IVIR-AC).

/Courtesy of The Conversation. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).