UK Reports 2024 Animal Research Statistics

The 10 organisations in Great Britain that carry out the highest number of animal procedures - those used in medical, veterinary and scientific research - have released their annual statistics today.

Animal research... is an essential step in the development of new medicines, vaccines and treatments for both humans and animals.

Jon Simons

The statistics for the University of Cambridge are available on our website as part of our ongoing commitment to transparency and openness around the use of animals in research.

This coincides with the publication of the Home Office report on the statistics of scientific procedures on living animals in Great Britain in 2024.

The 10 organisations are listed below alongside the total number of procedures they carried out on animals for scientific research in Great Britain in 2024. Of these 1,379,399 procedures, more than 99% were carried out on mice, fish, rats, and birds and 82% were classified as causing pain equivalent to, or less than, an injection.

This is the tenth consecutive year that organisations have come together to publicise their collective statistics and examples of their research.

OrganisationNumber of Procedures (2024)
The Francis Crick Institute200,055
University of Oxford199,730
University of Cambridge190,448
UCL175,687
Medical Research Council140,602
University of Edinburgh136,862
King's College London106,300
University of Glasgow99,509
University of Manchester81,252
Imperial College London48,954
TOTAL1,379,399

In total, 72 organisations have voluntarily published their 2024 animal research statistics.

All organisations are committed to the ethical framework called the '3Rs' of replacement, reduction and refinement. This means avoiding or replacing the use of animals where possible, minimising the number of animals used per experiment and optimising the experience of the animals to improve animal welfare. However, as institutions expand and conduct more research, the total number of animals used can rise even if fewer animals are used per study.

All organisations listed are signatories to the Concordat on Openness on Animal Research in the UK, which commits them to being more open about the use of animals in scientific, medical and veterinary research in the UK. More than 130 organisations have signed the Concordat, including UK universities, medical research charities, research funders, learned societies and commercial research organisations.

Wendy Jarrett, Chief Executive of Understanding Animal Research, which developed the Concordat on Openness, said: "Animal research remains a small but vital part of the quest for new medicines, vaccines and treatments for humans and animals. Alternative methods are increasingly being phased in, but, until we have sufficient reliable alternatives available, it is important that organisations that use animals in research maintain the public's trust in them. By providing this level of information about the numbers of animals used, and the experience of those animals, as well as details of the medical breakthroughs that derive from this research, these Concordat signatories are helping the public to make up their own minds about how they feel about the use of animals in scientific research in Great Britain."

Professor Jon Simons, Head of the School of Biological Sciences at the University of Cambridge, said: "Animal research remains critical for understanding complex biological systems and is an essential step in the development of new medicines, vaccines and treatments for both humans and animals. We are committed to continuing to reduce the number of animals used in biomedical research, and our scientists are actively working on new methods and techniques that will provide robust scientific alternatives."

Text adapted from a press release by Understanding Animal Research.

CASE STUDY: Mice are vital in the search for effective new dementia treatments

Cambridge researchers are leading drug discovery to develop safer, more effective treatments for the millions of people affected by Alzheimer's and other neurodegenerative diseases.

"Dementia has often been viewed as something that happens normally as people age, but it's not. It's a disease that we need to treat, so that people can live well and stay independent in later life," said David Harrison. "But many pharmaceutical companies have lost confidence in working in this area because the risk of failure is too great."

With expertise in drug discovery, Harrison's team at Cambridge's ALBORADA Drug Discovery Institute is designing and making chemical molecules - the basis of future drugs - and testing whether they work on novel targets in the body. The aim is to develop these ideas to the point where pharmaceutical partners can more confidently take things forward.

While the team routinely uses test-tube and computer-based models, animal models are vital in understanding how the many different cell types in the brain interact together in disease.

They're also vital in understanding how potential drugs are metabolised and distributed throughout the body, and in looking for any adverse effects that may occur in other tissues.

Harrison said: "Almost one million people are estimated to be living with dementia in the UK. We need to find better treatment options. The animals we use are an essential part of the drug discovery process - they could help us change people's lives."

Read the full story here

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