MD Anderson Research Highlights July 19, 2023

University of Texas M. D. Anderson Cancer Center

HOUSTON ― The University of Texas MD Anderson Cancer Center's Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson's world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

Recent developments include promising results from combining immunotherapy with radiation for non-small cell lung cancer (NSCLC), a novel combination therapy for secondary and treatment-resistant blood cancers, understanding the prognostic value of splicing factor gene mutations in AML, an approach to overcoming treatment resistance in HR-positive/HER2-negative metastatic breast cancer, a new treatment strategy for metastatic appendix cancer, improved survival outcomes for young adults with multiple myeloma, a preventive treatment to lessen toxicities from chimeric antigen receptor (CAR) T cell therapy, and the use of artificial intelligence to improve prognostic models for patients with cancer.

Read this press release on the MD Anderson newsroom.

Immunotherapy plus targeted radiation improved lung cancer outcomes compared to radiation alone

Standard treatment for inoperable early stage non-small cell lung cancer (NSCLC) is a form of targeted radiation called stereotactic ablative radiotherapy (SABR), but relapses remain common. Results from a Phase II randomized study, led by Joe Chang, M.D., Ph.D., and John Heymach, M.D., Ph.D., found combining SABR with immunotherapy

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